Top 12 Supplements for Brain Healing & Neurological Health (with Science-Backed Benefits)

When it comes to brain health, the right supplements can make a powerful difference. Whether you're recovering from a brain injury, supporting cognitive resilience, or simply optimizing your mental performance, certain nutrients help reduce inflammation, promote neuroplasticity, and protect your brain’s structure and function.

In this post, you'll find some of the most science-supported supplements for neurological healing — with links to high-quality products I personally recommend (affiliate links included).

Disclosure: As an Amazon Associate, I may earn from qualifying purchases. This comes at no extra cost to you and helps support the continued creation of helpful, research-backed content.

Give your brain the gift of neuroprotection.

🧠 Top Supplements for Brain Healing & Neuroprotection:

1. Omega-3 Fatty Acids (DHA & EPA)

• Found in fish oil, krill oil, and algae-based supplements

• Reduces inflammation, protects neurons, and supports the myelin sheath

• DHA is especially important for memory and cognitive performance

• 🔹 Suggested Dose: 1,000–3,000 mg daily

• 👉 Try Pure Encapsulations - Fish Oil - https://amzn.to/4hX2ASe (US)

• 👉 Or try Vegan Omega-3 - https://amzn.to/3E2nTnw (US)

2. Phosphatidylserine (PS)

• Supports healthy cell membranes and neurotransmitter function

• Enhances focus, memory, and stress resilience

• Helps regulate cortisol levels

• 🔹 Suggested Dose: 100–300 mg daily

• 👉 Try Thorne Phosphatidylserine capsules (from soy) - https://amzn.to/4iDgUjR (US)

• 👉 Or Soy-Free Phosphatidyleerine from NOW Foods - https://amzn.to/3FAHagh (US)

3. Acetyl-L-Carnitine (ALCAR)

• Boosts brain energy by supporting mitochondria

• Enhances dopamine and acetylcholine production

• Useful for neuroprotection and mental stamina

• 🔹 Suggested Dose: 500–2,000 mg daily

• 👉 Try Designs for Health Acetyl L Carnitine - https://amzn.to/4l18JQ7 (US)

• 👉 Or Designs for Health Brain Vitale - https://amzn.to/3FzW3PY (US)

  • Contains Phosphatidylserine, ginkgo biloba, Acetyl L Carnitine, Citicoline, and glycerophosphocholine (GPC). This powerful blend supports memory, focus, and cognitive resilience by enhancing neurotransmitter function, brain circulation, and cellular energy.

4. Lion’s Mane Mushroom 🍄

• Stimulates nerve growth factor (NGF)

• Promotes memory, learning, and neural regeneration

• Often used for cognitive decline and brain injury recovery

• 🔹 Suggested Dose: 500–3,000 mg (standardized extract)

• 👉 Try NOW Foods Lion’s Mane capsules - https://amzn.to/4hjmve6 (US)

• 👉 Or Nootropics Lion’s Mane Mycelium capsules - https://amzn.to/3DSCfH7 (US)

• 👉 Or E2H Lion’s Mane tincture - https://amzn.to/41Z7zMf (US)

5. Magnesium L-Threonate

• Crosses the blood-brain barrier more effectively than other forms

• Improves memory, clarity, and synaptic function

• May help reduce anxiety and brain fog

• 🔹 Suggested Dose: 1,000–2,000 mg daily

• 👉 Try Designs for Health NeuroMag Magnesium L-Threonate (chelated) - https://amzn.to/3FBZ9TL (US)

• 👉 Or CYMBIOTIKA Magnesium L-Threonate (liposomal travel pouches) - https://amzn.to/4bGT7gG (US)

6. N-Acetyl Cysteine (NAC)

• Increases glutathione, the brain’s master antioxidant

• Powerful support for OCD, addiction, and TBI recovery

• Reduces oxidative stress and neuroinflammation

• 🔹 Suggested Dose: 600–1,800 mg

• 👉 Try Now Foods NAC capsules - https://amzn.to/4c1kfHb (US)

• 👉 Or ETTA VITA NAC capsules - https://amzn.to/4j02tGr (US)

  • Also contains Quercetin, Milk Thistle, Molybdenum & Selenium, enhancing NAC’s detoxifying and neuroprotective effects by supporting antioxidant activity, liver function, and cellular repair.

7. Alpha-GPC or CDP-Choline (Citicoline)

• Enhances memory and focus through acetylcholine production

• Aids neuroplasticity and brain repair

• Also supports dopamine pathways

• 🔹 Suggested Dose: 300–600 mg

• 👉 Try Designs for Health Alpha GPC Liquid drops - https://amzn.to/4bYpVle (US)

• 👉 Or NOW Foods Alpha GPC capsules - https://amzn.to/3DPhDj0 (US)

• 👉 Or Nutricost CDP Choline capsules - https://amzn.to/42a1Rsl (US)

8. Curcumin (Turmeric Extract)

• Reduces inflammation and supports BDNF levels

• Useful for depression, cognitive decline, and brain injury

• Look for one with black pepper extract (piperine) for absorption

• 🔹 Suggested Dose: 500–1,500 mg daily

• 👉 Try Designs for Health C3 Curcumin Complex (Highly Bioavailable) - https://amzn.to/43VdzZ3 (US)

• 👉 Or Ultra Premium Turmeric Curcumin with Black Pepper Extract capsules - https://amzn.to/42dRN1p (US)

• 👉 Or Smarter Nutrition Curcumin Softgels + Organic Black Seed Oil & Ginger - https://amzn.to/4iYtkml (US)

  • Black seed oil and ginger enhance Curcumin’s anti-inflammatory effects and improve absorption for deeper joint, brain, and immune support.

9. CoQ10 or Ubiquinol

• Enhances energy production in brain cells

• Protects against oxidative damage and aging

• Supports neurodegenerative recovery

• 🔹 Suggested Dose: 100–300 mg

• 👉 Try Designs for Health CoQnol Softgels - https://amzn.to/41An7WL (US)

• 👉 Or NOW Foods Supplements CoQ10 Veg Capsules - https://amzn.to/4hmYjrd (US)

10. B Vitamins (B6, B9, B12)

• Crucial for neurotransmitter production and myelin health

• Prevents brain atrophy and high homocysteine levels (linked to dementia)

• 🔹 Suggested Dose:

  • B6: 10–50 mg

  • B9: 400–800 mcg

  • B12: 1,000 mcg (methylcobalamin preferred)

• 👉 Try Pure Encapsulations B-Complex Plus Capsules - https://amzn.to/4iYujTz (US)

• 👉 Or Earth Harmony Vegan B12 Sublingual Liquid - https://amzn.to/4bKvIuM (US)

• 👉 Or NutraHarmony Vitamin B-Complex Liquid Drops - https://amzn.to/4iU5OHa (US)

• 👉 Or Igennus Super B-Complex Methylated B Vitamins & Vitamin C - https://amzn.to/41yFbk5

  • Vitamin C supports the absorption and effectiveness of B vitamins while boosting antioxidant protection and energy metabolism.

11. Creatine

• Supports ATP (energy) in the brain

• Improves mental clarity and resilience

• Especially useful for TBI recovery and high-stress states

• 🔹 Suggested Dose: 3–5 grams daily

• 👉 Try Designs for Health Creatine Monohydrate powder - https://amzn.to/3RjhqYo (US)

• 👉 Or Metagenics Creatine Monohydrate powder - https://amzn.to/4hlOgmj (US)

12. L-Theanine

• Naturally found in green tea

• Promotes calm alertness and increases alpha brain waves

• Synergistic with caffeine for a focused boost

• 🔹 Suggested Dose: 100–400 mg

• 👉 Try Pure Encapsulations L-Theanine Capsules - https://amzn.to/4bBltsA (US)

• 👉 Or Designs for Health NeuroCalm Capsules - https://amzn.to/3DQOLa2 (US)

  • Contains 5HTP, GABA, and L-Theanine to promote calm focus, plus Methylated B12, Vitamin B6, Taurine, Chamomile & Magnesium to support nervous system balance and a healthy stress response.

• 👉 Or Designs for Health Liposomal NeuroCalm - Liquid GABA + L-Theanine - https://amzn.to/4iyfEyE (US)

  • This fast-absorbing liquid formula combines GABA and L-Theanine to support relaxation, mental clarity, and a calm stress response.

🧩 Additional Lifestyle Tools for Brain Health

Alongside supplements, these strategies support a healthy, resilient brain:

✅ Cold exposure & sauna — boost BDNF and neurogenesis

✅ Intermittent fasting — supports brain repair & inflammation reduction

✅ Exercise (aerobic & strength) — raises BDNF levels

✅ Breathwork & meditation — increase neuroplasticity and reduce stress

💡 Final Thoughts:

You don't need to take all of these at once — start with the supplements that best match your goals or challenges. Always check with a healthcare provider before starting new protocols, especially if you're taking medication or managing a neurological condition.

Disclosure: As an Amazon Associate, I earn from qualifying purchases. I only recommend products I trust and have either used personally or thoroughly researched.